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What is 1P-LSD?

If you’re interested in psychedelics, you’ve probably heard of LSD. But what about 1P-LSD? What’s the difference between these two substances? Here’s an in depth overview to help you better understand the key distinctions.

1P-LSD is a semi-synthetic compound that is derived from lysergic acid. This substance is considered to be a potent agonist of the 5HT2A receptor. 1P-LSD is also similar in structure to LSD, which is why it is sometimes referred to as "mini-LSD" or "microdosing LSD." However, it should be noted that 1P-LSD has not been studied as extensively as LSD and its effects are not fully understood. Therefore, it is important to approach this substance with caution.

1P-LSD vs LSD: What’s the Difference?

1P-LSD is a newer substance that’s similar to LSD. Both of these substances are considered psychedelics, meaning they can produce changes in perception, mood, and cognition. However, there are some important differences to be aware of.

For one, LSD is more potent than 1P-LSD. This means that it takes less LSD to produce the desired effects. Additionally, LSD is longer lasting; its effects can last up to 12 hours, while 1P-LSD’s effects only last for 4-6 hours. Finally, LSD is more likely to produce visual hallucinations; 1P-LSD is less likely to do so.

Legalities: LSD is an illegal drug in most countries. 1P LSD is a research chemical and is legal.

Effects: 1P LSD may be more stimulating and fast-paced in regard to its physical and cognitive effects. However, overall, the average user expresses that they cannot tell the difference.

Both LSD and 1P-LSD can produce powerful changes in perception and cognition, so similar preparation is required. 


Full breakdown here

The exact mechanism of action of 1P LSD is not fully understood, but it is thought to work by binding to serotonin receptors in the brain. Serotonin is a neurotransmitter that plays a role in mood, perception, and cognition. By binding to serotonin receptors, 1P LSD alters perception and produces the hallucinogenic effects that are characteristic of this drug.

A study from 2015 indicated that 1P-LSD shows 38% the potency of LSD in mice, though the drug did exhibit LSD-like behavior. 

1P LSD is a very potent drug, and it can produce intense visual and auditory hallucinations. Users will also experience changes in mood, perception, and cognition. 

How to take 1P-LSD

1P-LSD can be taken orally, sublingually, or rectally. The preferred method of administration will vary depending on the individual's tolerance and preference. Oral administration is the most common method, as it is the easiest to perform and has a relatively long duration of action. Sublingual administration is less common but may be more effective, as it allows for more rapid absorption into the bloodstream. 

For oral administration, simply place the desired amount of 1P-LSD onto your tongue and swallow. The effects will begin to kick in after 30-60 minutes and will peak around 2-4 hours after ingestion. The total duration of action will typically be between 6 and 12 hours, although this can vary depending on individual tolerance and metabolism.

For sublingual administration, place the desired amount of 1P-LSD under your tongue and hold it there for 5-10 minutes before swallowing. The effects will begin to kick in after 15-30 minutes and will peak around 2-4 hours after ingestion. The total duration of action will typically be between 6 and 12 hours, although this can vary depending on individual tolerance and metabolism.

What are the effects of 1P-LSD?

The 1P-LSD experience is commonly reported to be virtually indistinguishable from LSD-25: 

  • Altered states of consciousness
  • Hallucinations
  • Changes in visual perception
  • Changes in auditory perception
  • Changes in taste and smell perception
  • Changes in body temperature
  • Increased heart rate and blood pressure
  • Dilated pupils

1P-LSD produces feelings of euphoria, feelings of openness, increased awareness, and spiritual experiences. Some people have reported a stronger body load and sense of time dilation than what they’ve experienced on LSD-25. Some psychonauts state 1P-LSD is less of a visual trip than LSD-25, while others couldn’t tell the difference in terms of visual effects.

The effects typically last for 6-8 hours.

One user on Erowid gave the following fairly magnificent description of their peak experience: 

I stood up and began to feel this warm feeling in my head. I spoke and said “Somehow I am aware that I exist, and I do exist at this very moment in time but most of the time I have not existed. Existence is such a delicate and special phenomenon because I will not always exist. I should do something meaningful with this existence”.I felt myself becoming more and more emotional until I cried about how amazing it was that I exist at this very moment. We continued walking and eventually noticed the sun start to come out. I pointed my head toward the sun and felt the sun shatter my body into molecules like shattering glass. These molecules that were me fell into a puddle to water and I became the water. I looked up at myself as if I were these water molecules. As I looked up at myself the water molecules that were me traveled up and were absorbed into my body. I began to cry again at how amazing this experience was. At that moment in time, I was completely dissociated from my real body. Nothing else mattered or existed I was just completely experiencing this cathartic moment. I started to talk to Sloan again " I'm just 1/7 billion consciousnesses that exist is my existence meaningful? I'm amazed that every alive person has a consciousness like me that seems so complex where does that come from. Sloan "Consciousness must arise out of all the complex brain interactions spontaneously." It started to get foggy out and the tide was slowly swallowing up the ocean floor. The fog was disorienting to me as I began to become confused about where I was in 3-dimensional space. Luckily, Sloan was sober and with me which gave me the freedom to act like an infant splashing around in the water and sand.

lP-LSD Dosage

A common dose range for 1P-LSD is 50-125 MCG. Most vendors sell tabs that are dosed at 100mcg per blotter tabs. 

The right dose for you can vary depending on many factors, including individual variability and tolerance levels. 

Strong doses generally range from 125-300 MCG, while heavy doses are above 300 MCG.  

Microdosing lP-LSD

Similar to LSD, Microdosing 1P-LSD has been reported to increase creativity, focus, and well-being.

A common starting microdose for 1P-LSD is 15 MCG. This can be titrated up depending on individual sensitivity and needs. Since 1P-LSD is less potent than LSD, those who microdose may require slightly more than the doses they are used to when micodosing LSD. 

How Long Does it Take for 1P-LSD to Kick In?

It usually takes around 40-90 minutes to begin to feel the effects. 

How long does 1P-LSD Trip last?

The effects of 1p-lsd typically last for 6-12 hours

Does 1P-LSD have a Comedown?

Users have reported after effects lasting about two hours and a comedown lasting up to 24 hours.

Is 1P-LSD Safe?

Generally, lysergamides are known for their high safety profile. 

As with any Psychedelic, it should be approached with caution, respect and 1p-lsd should be used with caution

What are the risks of 1P-LSD?

1P-LSD has the potential to cause anxiety, paranoia, and delusions AKA bad trips, just like other psychedelics. 

  • Nausea, vomiting, and diarrhea.
  • Increased bodily temperature.
  • Appetite suppression.
  • Dehydration.
  • Increased blood pressure/heart-rate/perspiration.
  • Time distortion.

Is 1p-LSD addictive?

1p-lsd is considered to be non-addictive and does not produce withdrawal symptoms when users stop taking the drug.

Is 1p-LSD legal?

1p-lsd is not currently scheduled as a controlled substance in the United States, but it is illegal to manufacture, possess, or sell 1p-lsd without a license.

Does 1P LSD Show Up on a Drug Test?

Yes, but only on an LSD drug test. LSD only shows up a maximum of 48 hours after ingestion in urine. 

Where can you buy 1p-LSD?

1P-LSD has been sold online as a research chemical (also called "designer drug") since 2015. 

You can find it relatively easily with a quick search - for example, in Canada you can visit stores like this

Online forums, such as the 1P-LSD subreddit, frequently discuss the most reliable current vendors.

Final Notes

The experience of taking 1p-lsd can be powerful, and it is important to be prepared before taking the drug (as is the case with any Psychedelic). You should also be sure to get 1P-LSD from a reliable source and take it in a safe setting.

There are a number of online forums where people who have taken 1p-lsd have shared their experiences, and these can be a valuable resource for anyone considering taking the drug. Check out the Erowid vault for a huge library of experiences. 


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